26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody

26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody is a Rabbit Polyclonal against 26S Proteasome Regulatory Subunit 10B (PSMC6). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Target	26S Proteasome Regulatory Subunit 10B (PSMC6)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthesized peptide derived from the Internal region of human PSMC6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P62333 (UniProt, ExPASy)
UniProt Secondary AC	B2R975, P49719, Q6IBU3, Q92524
UniProt Entry Name	PRS10_HUMAN
Gene Symbol	PSMC6
GeneID	5706
OMIM	602708
HGNC	9553
KEGG	hsa:5706
Ensembl	ENSG00000100519
String	9606.ENSP00000401802
Buffer	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Regulatory Subunit 10B (PSMC6)

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