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26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody
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Catalogue No: abx031717
Price:
US$326.25
(Size: 80 µl)
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26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody is a Rsbbit Policlonal against 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11). The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 288-317 amino acids from the C-terminal region of human PSMD11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00231 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3I7, E1P663, O00495, Q53FT5 |
| UniProt Entry Name | PSD11_HUMAN |
| Gene Symbol | PSMD11 |
| GeneID | 5717 |
| OMIM | 604449 |
| NCBI Accession | NP_001257411.1 NM_001270482.1 |
| HGNC | 9556 |
| KEGG | hsa:5717 |
| Ensembl | ENSG00000108671 |
| String | 9606.ENSP00000261712 |
| Molecular Weight | Calculated MW: 47.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow PSMD11. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
