26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7) Antibody

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Catalogue No: abx031787
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
PSMD7 acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Target 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PSMD7.
Isotype IgG
Form Liquid
Purification Purified Rabbit Polyclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P51665 (UniProt, ExPASy)
UniProt Secondary AC D3DWS9, Q6PKI2, Q96E97
UniProt Entry Name PSMD7_HUMAN
Gene Symbol PSMD8
GeneID 5713
OMIM 157970
HGNC 9565
KEGG hsa:5713
Ensembl ENSG00000103035
String 9606.ENSP00000219313
Molecular Weight Calculated MW: 37 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Cow PSMD7.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)


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