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Proteasome Inhibitor Subunit 1 (PSMF1) Antibody
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Catalogue No: abx004253
Price:
US$217.50
(Size: 20 µl)
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PSMF1 Antibody is a Rabbit Polyclonal antibody against PSMF1. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Research Articles on Proteasome Inhibitor Subunit 1 (PSMF1)
| Target | Proteasome Inhibitor Subunit 1 (PSMF1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human PSMF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92530 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AVQ9, D3DVW3, Q9H4I1 |
| UniProt Entry Name | PSMF1_HUMAN |
| Gene Symbol | PSMF1 |
| GeneID | 9491 |
| NCBI Accession | NP_006805.2 |
| KEGG | hsa:9491 |
| String | 9606.ENSP00000338039 |
| Molecular Weight | Calculated MW: 30 kDa Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |