Protein Tyrosine Kinase 6 (PTK6) Antibody

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation.

Target	Protein Tyrosine Kinase 6 (PTK6)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human PTK6 expressed in E. coli.
Isotype	IgG2b
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13882 (UniProt, ExPASy)
UniProt Secondary AC	B2RCR3, B4DW46, Q58F01
UniProt Entry Name	PTK6_HUMAN
Gene Symbol	PTK6
GeneID	5753
OMIM	602004
HGNC	9617
KEGG	hsa:5753
Ensembl	ENSG00000101213
String	9606.ENSP00000442460
Enzyme Commission Number	EC 2.7.10.2
Molecular Weight	52 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Tyrosine Kinase 6 (PTK6)

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