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Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) Antibody
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Catalogue No: abx011792
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTPN11 (AA: 263-329) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06124 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1D9, Q96HD7 |
| UniProt Entry Name | PTN11_HUMAN |
| Gene Symbol | PTPN11 |
| GeneID | 5781 |
| OMIM | 151100 |
| HGNC | 9644 |
| KEGG | hsa:5781 |
| Ensembl | ENSG00000179295 |
| String | 9606.ENSP00000340944 |
| Molecular Weight | 68.4 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |