Tyrosine-Protein Phosphatase Non-Receptor Type 14 (PTPN14) Antibody

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.

Target	Tyrosine-Protein Phosphatase Non-Receptor Type 14 (PTPN14)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 862-890 amino acids from the C-terminal region of human PTPN14.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15678 (UniProt, ExPASy)
UniProt Secondary AC	Q5VSI0
UniProt Entry Name	PTN14_HUMAN
KEGG	hsa:5784
String	9606.ENSP00000355923
Molecular Weight	Calculated MW: 135 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tyrosine-Protein Phosphatase Non-Receptor Type 14 (PTPN14)

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