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Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody
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Catalogue No: abx001222
Price:
US$203.00
(Size: 20 µl)
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PTPN22 Antibody is a Rabbit Polyclonal antibody against PTPN22. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y2R2 (UniProt, ExPASy) |
| UniProt Entry Name | PTN22_HUMAN |
| Gene Symbol | PTPN22 |
| GeneID | 26191 |
| NCBI Accession | NP_036543.4 |
| String | 9606.ENSP00000352833 |
| Molecular Weight | Calculated MW: 92 kDa Observed MW: 107 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |