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Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7) Antibody
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Catalogue No: abx002985
Price:
US$217.50
(Size: 20 µl)
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PTPN7 Antibody is a Rabbit Polyclonal antibody against PTPN7. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PTPN7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35236 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KXE1, Q53XK4, Q5SXQ0, Q5SXQ1, Q9BV05 |
| UniProt Entry Name | PTN7_HUMAN |
| Gene Symbol | PTPN7 |
| GeneID | 5778 |
| NCBI Accession | NP_542155.1 |
| KEGG | hsa:5778 |
| String | 9606.ENSP00000309116 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |