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Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) Antibody
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Catalogue No: abx028034
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq].
Research Articles on Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE)
| Target | Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23469 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13345, Q5VWH3, Q5VWH4, Q96KQ6 |
| UniProt Entry Name | PTPRE_HUMAN |
| Gene Symbol | PTPRE |
| GeneID | 5791 |
| OMIM | 600926 |
| HGNC | 9669 |
| KEGG | hsa:5791 |
| Ensembl | ENSG00000132334 |
| String | 9606.ENSP00000254667 |
| Molecular Weight | Calculated MW: 80.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat PTPRE. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |