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6-Pyruvoyl Tetrahydrobiopterin Synthase (PTS) Antibody
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Catalogue No: abx004820
Price:
US$203.00
(Size: 20 µl)
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PTS Antibody is a Rabbit Polyclonal antibody against PTS. The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
Research Articles on 6-Pyruvoyl Tetrahydrobiopterin Synthase (PTS)
| Target | 6-Pyruvoyl Tetrahydrobiopterin Synthase (PTS) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q03393 (UniProt, ExPASy) |
| UniProt Secondary AC | B0YJ87, Q8WVG8 |
| UniProt Entry Name | PTPS_HUMAN |
| Gene Symbol | PTS |
| GeneID | 5805 |
| OMIM | 261640 |
| NCBI Accession | NP_000308.1 |
| HGNC | 9689 |
| KEGG | hsa:5805 |
| Ensembl | ENSG00000150787 |
| String | 9606.ENSP00000280362 |
| Molecular Weight | Calculated MW: 16 kDa Observed MW: 16 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |