+44 (0) 1223 755950
+1 832 327 7413
Poliovirus Receptor Related Protein 1 (PVRL1) Antibody
REQUEST MORE INFO
Catalogue No: abx001654
Price:
US$348.00
(Size: 60 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
PVRL1 Antibody is a Rabbit Polyclonal antibody against PVRL1. This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009].
Research Articles on Poliovirus Receptor Related Protein 1 (PVRL1)
| Target | Poliovirus Receptor Related Protein 1 (PVRL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PVRL1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15223 (UniProt, ExPASy) |
| UniProt Secondary AC | O75465, Q2M3D3, Q9HBE6, Q9HBW2 |
| UniProt Entry Name | NECT1_HUMAN |
| Gene Symbol | NECTIN1 |
| GeneID | 5818 |
| NCBI Accession | NP_002846.3 |
| KEGG | hsa:5818 |
| String | 9606.ENSP00000264025 |
| Molecular Weight | Calculated MW: 39 kDa/50 kDa/57 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |