Glycogen Phosphorylase, Brain (PYGB) Antibody

PYGB Antibody is a Rabbit Polyclonal antibody against PYGB. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.

Target	Glycogen Phosphorylase, Brain (PYGB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11216 (UniProt, ExPASy)
UniProt Secondary AC	Q96AK1, Q9NPX8
UniProt Entry Name	PYGB_HUMAN
Gene Symbol	PYGB
GeneID	5834
NCBI Accession	NP_002853.2
KEGG	hsa:5834
String	9606.ENSP00000216962
Molecular Weight	Calculated MW: 97 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycogen Phosphorylase, Brain (PYGB)

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