Quinoid Dihydropteridine Reductase (QDPR) Antibody

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Catalogue No: abx004384
Price: US$217.50
(Size: 20 µl)

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Datasheet SDS
QDPR Antibody is a Rabbit Polyclonal antibody against QDPR. This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Target Quinoid Dihydropteridine Reductase (QDPR)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P09417 (UniProt, ExPASy)
UniProt Secondary AC A8K158, B3KW71, Q53F52, Q9H3M5
UniProt Entry Name DHPR_HUMAN
Gene Symbol QDPR
GeneID 5860
NCBI Accession NP_000311.2
KEGG hsa:5860
String 9606.ENSP00000281243
Molecular Weight Calculated MW: 26 kDa
Observed MW: 26 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Quinoid Dihydropteridine Reductase (QDPR)