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Ras-Related Protein Rab-6A (RAB6A) Antibody
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Catalogue No: abx004290
Price:
US$217.50
(Size: 20 µl)
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RAB6A Antibody is a Rabbit Polyclonal antibody against RAB6A. This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Research Articles on Ras-Related Protein Rab-6A (RAB6A)
| Target | Ras-Related Protein Rab-6A (RAB6A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20340 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K133, B7Z772, F5H668, Q1W5D8, Q5U0A8, Q9UBE4 |
| UniProt Entry Name | RAB6A_HUMAN |
| Gene Symbol | RAB6A |
| GeneID | 5870 |
| OMIM | 179513 |
| NCBI Accession | NP_002860.2 |
| HGNC | 9786 |
| KEGG | hsa:5870 |
| Ensembl | ENSG00000175582 |
| String | 9606.ENSP00000311449 |
| Molecular Weight | Calculated MW: 24 kDa Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |