Rac-GTPase Activating Protein 1 (RACGAP1) Antibody

RACGAP1 Antibody is a Rabbit Polyclonal antibody against RACGAP1. The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.

Target	Rac-GTPase Activating Protein 1 (RACGAP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 353-632 of human RGAP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H0H5 (UniProt, ExPASy)
UniProt Secondary AC	Q6PJ26, Q9NWN2, Q9P250, Q9P2W2
UniProt Entry Name	RGAP1_HUMAN
Gene Symbol	RACGAP1
GeneID	29127
NCBI Accession	NP_001119576.1
String	9606.ENSP00000404190
Molecular Weight	Calculated MW: 71 kDa Observed MW: 71 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Rac-GTPase Activating Protein 1 (RACGAP1)

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