RAD1 Checkpoint DNA Exonuclease (RAD1) Antibody

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq].

Target	RAD1 Checkpoint DNA Exonuclease (RAD1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 118-146 amino acids from the Central region of human RAD1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O60671 (UniProt, ExPASy)
UniProt Secondary AC	O75572, O95304, Q1W161, Q5KSM0, Q5KSM1, Q9UEP1
UniProt Entry Name	RAD1_HUMAN
Gene Symbol	RAD1
KEGG	hsa:5810
String	9606.ENSP00000371469
Molecular Weight	Calculated MW: 31.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RAD1 Checkpoint DNA Exonuclease (RAD1)

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