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RAD18, E3 Ubiquitin Protein Ligase (RAD18) Antibody
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Catalogue No: abx004120
Price:
US$203.00
(Size: 20 µl)
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RAD18 Antibody is a Rabbit Polyclonal antibody against RAD18. The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Research Articles on RAD18, E3 Ubiquitin Protein Ligase (RAD18)
| Target | RAD18, E3 Ubiquitin Protein Ligase (RAD18) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human Rad18. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NS91 (UniProt, ExPASy) |
| UniProt Secondary AC | Q58F55, Q9NRT6 |
| UniProt Entry Name | RAD18_HUMAN |
| Gene Symbol | RAD18 |
| GeneID | 56852 |
| NCBI Accession | NP_064550.3 |
| String | 9606.ENSP00000264926 |
| Molecular Weight | Calculated MW: 56 kDa Observed MW: 80 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |