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RAD51 Recombinase (RAD51) Antibody
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Catalogue No: abx004788
Price:
US$203.00
(Size: 20 µl)
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RAD51 Antibody is a Rabbit Polyclonal antibody against RAD51. The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on RAD51 Recombinase (RAD51)
| Target | RAD51 Recombinase (RAD51) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human Rad51. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06609 (UniProt, ExPASy) |
| UniProt Secondary AC | B0FXP0, B2R8T6, Q6FHX9, Q6ZNA8, Q9BV60 |
| UniProt Entry Name | RAD51_HUMAN |
| Gene Symbol | RAD51 |
| GeneID | 5888 |
| NCBI Accession | NP_002866.2 |
| KEGG | hsa:5888 |
| Molecular Weight | Calculated MW: 37 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |