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RAD51 Paralog C (RAD51C) Antibody
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Catalogue No: abx028449
Price:
US$326.25
(Size: 80 µl)
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This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
Research Articles on RAD51 Paralog C (RAD51C)
| Target | RAD51 Paralog C (RAD51C) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43502 (UniProt, ExPASy) |
| UniProt Secondary AC | O43503, Q3B783 |
| UniProt Entry Name | RA51C_HUMAN |
| Gene Symbol | RAD51C |
| KEGG | hsa:5889 |
| String | 9606.ENSP00000336701 |
| Molecular Weight | Calculated MW: 42.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |