RAD51 Paralog C (RAD51C) Antibody

RAD51C Antibody is a Rabbit Polyclonal antibody against RAD51C. This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Target	RAD51 Paralog C (RAD51C)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43502 (UniProt, ExPASy)
UniProt Secondary AC	O43503, Q3B783
UniProt Entry Name	RA51C_HUMAN
Gene Symbol	RAD51C
GeneID	5889
NCBI Accession	NP_002867.1
KEGG	hsa:5889
String	9606.ENSP00000336701
Molecular Weight	Calculated MW: 42 kDa Observed MW: 42 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RAD51 Paralog C (RAD51C)

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