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RAD51 Paralog B (RAD51L1) Antibody
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Catalogue No: abx005281
Price:
US$217.50
(Size: 20 µl)
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RAD51L1 Antibody is a Rabbit Polyclonal antibody against RAD51L1. The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Research Articles on RAD51 Paralog B (RAD51L1)
| Target | RAD51 Paralog B (RAD51L1) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human RAD51B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15315 (UniProt, ExPASy) |
| UniProt Entry Name | RA51B_HUMAN |
| Gene Symbol | RAD51B |
| GeneID | 5890 |
| NCBI Accession | NP_598193.2 |
| KEGG | hsa:5890 |
| String | 9606.ENSP00000419471 |
| Molecular Weight | Calculated MW: 42 kDa Observed MW: 42 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |