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Ribonucleic Acid Export 1 (RAE1) Antibody
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Catalogue No: abx005150
Price:
US$203.00
(Size: 20 µl)
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RAE1 Antibody is a Rabbit Polyclonal antibody against RAE1. Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Research Articles on Ribonucleic Acid Export 1 (RAE1)
| Target | Ribonucleic Acid Export 1 (RAE1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human RAE1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P78406 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K882, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6 |
| UniProt Entry Name | RAE1L_HUMAN |
| Gene Symbol | RAE1 |
| GeneID | 8480 |
| NCBI Accession | NP_003601.1 |
| KEGG | hsa:8480 |
| String | 9606.ENSP00000379182 |
| Molecular Weight | Calculated MW: 41 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |