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Receptor Activity Modifying Protein 1 (RAMP1) Antibody
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Catalogue No: abx004940
Price:
US$217.50
(Size: 20 µl)
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RAMP1 Antibody is a Rabbit Polyclonal antibody against RAMP1. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Research Articles on Receptor Activity Modifying Protein 1 (RAMP1)
| Target | Receptor Activity Modifying Protein 1 (RAMP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 21-120 of human RAMP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60894 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6FGS5 |
| UniProt Entry Name | RAMP1_HUMAN |
| Gene Symbol | RAMP1 |
| GeneID | 10267 |
| NCBI Accession | NP_005846.1 |
| KEGG | hsa:10267 |
| String | 9606.ENSP00000254661 |
| Molecular Weight | Calculated MW: 17 kDa Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |