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Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) Antibody
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Catalogue No: abx029260
Price:
US$326.25
(Size: 80 µl)
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Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).
Research Articles on Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5)
| Target | Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92565 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D140, Q8IXU5 |
| UniProt Entry Name | RPGF5_HUMAN |
| KEGG | hsa:9771 |
| String | 9606.ENSP00000343656 |
| Molecular Weight | Calculated MW: 67.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |