RasGAP-Activating-Like Protein 1 (RASAL1) Antibody

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Catalogue No: abx026830
Price: US$326.25
(Size: 80 µl)

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RasGAP-Activating-Like Protein 1 (RASAL1) Antibody
RasGAP-Activating-Like Protein 1 (RASAL1) Antibody

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Datasheet SDS
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Target RasGAP-Activating-Like Protein 1 (RASAL1)
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O95294 (UniProt, ExPASy)
UniProt Secondary AC B7ZKM4, C9JFK5, F8VQX1, Q52M03, Q59H24, Q96CC7
UniProt Entry Name RASL1_HUMAN
Gene Symbol RASAL1
KEGG hsa:8437
String 9606.ENSP00000450244
Molecular Weight Calculated MW: 90 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on RasGAP-Activating-Like Protein 1 (RASAL1)
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