Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1) Antibody

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Catalogue No: abx033491
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Target Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 907-936 amino acids from human RASGRF1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13972 (UniProt, ExPASy)
UniProt Secondary AC F8VPA5, H0YKF2, J3KQP9, Q16027
UniProt Entry Name RGRF1_HUMAN
Gene Symbol RASGRF1
GeneID 5923
OMIM 606600
HGNC 9875
KEGG hsa:5923
Ensembl ENSG00000058335
String 9606.ENSP00000405963
Molecular Weight Calculated MW: 145 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1)
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