+44 (0) 1223 755950
+1 832 327 7413
rat TSC1 (pS312) Antibody
REQUEST MORE INFO
Catalogue No: abx032238
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Research Articles on TSC1 (pS312)
| Target | TSC1 (pS312) |
| Clonality | Polyclonal |
| Target Modification | Ser312 |
| Modification | Phosphorylation |
| Reactivity | Rat |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Z136 (UniProt, ExPASy) |
| UniProt Entry Name | TSC1_RAT |
| String | 10116.ENSRNOP00000016904 |
| Molecular Weight | Calculated MW: 129 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |