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RB (pS612) Antibody
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Catalogue No: abx031908
Price:
US$326.25
(Size: 80 µl)
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Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.[supplied by OMIM].
Research Articles on RB (pS612)
| Target | RB (pS612) |
| Clonality | Polyclonal |
| Target Modification | Ser612 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06400 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K5E3, P78499, Q5VW46, Q8IZL4 |
| UniProt Entry Name | RB_HUMAN |
| NCBI Accession | NP_000312.2 |
| KEGG | hsa:5925 |
| String | 9606.ENSP00000267163 |
| Molecular Weight | Calculated MW: 106 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |