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Retinoblastoma Protein 1 (RB1) Antibody
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Catalogue No: abx034004
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
Research Articles on Retinoblastoma Protein 1 (RB1)
| Target | Retinoblastoma Protein 1 (RB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06400 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K5E3, P78499, Q5VW46, Q8IZL4 |
| UniProt Entry Name | RB_HUMAN |
| KEGG | hsa:5925 |
| String | 9606.ENSP00000267163 |
| Molecular Weight | Calculated MW: 106 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat RB1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |