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Calcipressin-1 (RCAN1) Antibody
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Catalogue No: abx029066
Price:
US$290.00
(Size: 80 µl)
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The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Research Articles on Calcipressin-1 (RCAN1)
| Target | Calcipressin-1 (RCAN1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P53805 (UniProt, ExPASy) |
| UniProt Entry Name | RCAN1_HUMAN |
| KEGG | hsa:1827 |
| String | 9606.ENSP00000370527 |
| Molecular Weight | Calculated MW: 28.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse RCAN1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |