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Calcipressin-1 (RCAN1) Antibody
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Catalogue No: abx004072
Price:
US$203.00
(Size: 20 µl)
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RCAN1 Antibody is a Rabbit Polyclonal antibody against RCAN1. The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Research Articles on Calcipressin-1 (RCAN1)
| Target | Calcipressin-1 (RCAN1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of human RCAN1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P53805 (UniProt, ExPASy) |
| UniProt Entry Name | RCAN1_HUMAN |
| Gene Symbol | RCAN1 |
| GeneID | 1827 |
| NCBI Accession | NP_004405.3 |
| KEGG | hsa:1827 |
| String | 9606.ENSP00000370527 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 31 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.79 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |