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REA Antibody
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Catalogue No: abx033285
Price:
US$290.00
(Size: 80 µl)
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PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER) selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
Research Articles on REA
| Target | REA |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human REA (PHB2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99623 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DP75, Q2YDA4, Q7KYU3, Q92978 |
| UniProt Entry Name | PHB2_HUMAN |
| KEGG | hsa:11331 |
| String | 9606.ENSP00000441875 |
| Molecular Weight | Calculated MW: 33.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Chicken PHB2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |