Regenerating Islet Derived Protein 1 Alpha (REG1A) Antibody

REG1A (regenerating islet-derived 1 alpha), also known as PTP, PSP, is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis.Due to variable glycosylation, pancreatic REG1A exists as multiple species of 16 - 18 kDa. REG1A promotes the maintenance and growth of pancreatic islet beta cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes.

Target	Regenerating Islet Derived Protein 1 Alpha (REG1A)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human REG1A fused with hIgGFc tag expressed in HEK293 cell line.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05451 (UniProt, ExPASy)
UniProt Secondary AC	P11379, Q4ZG28
UniProt Entry Name	REG1A_HUMAN
Gene Symbol	REG1A
GeneID	5967
OMIM	167770
HGNC	9951
KEGG	hsa:5967
Ensembl	ENSG00000115386
String	9606.ENSP00000233735
Molecular Weight	19 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Regenerating Islet Derived Protein 1 Alpha (REG1A)

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