Regulator Of G Protein Signaling 5 (RGS5) Antibody

This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target	Regulator Of G Protein Signaling 5 (RGS5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human RGS5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15539 (UniProt, ExPASy)
UniProt Secondary AC	E9PMP5, Q53XA9, Q599J0
UniProt Entry Name	RGS5_HUMAN
Gene Symbol	RGS5
KEGG	hsa:8490
String	9606.ENSP00000433001
Molecular Weight	Calculated MW: 20.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Regulator Of G Protein Signaling 5 (RGS5)

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