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Prorelaxin H1/2 (RLN1/RLN2) Antibody
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Catalogue No: abx027652
Price:
US$326.25
(Size: 80 µl)
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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet. [provided by RefSeq].
Research Articles on Prorelaxin H1/2 (RLN1/RLN2)
| Target | Prorelaxin H1/2 (RLN1/RLN2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human RLN1/RLN2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04808 (UniProt, ExPASy) |
| UniProt Secondary AC | Q99936, Q9UQJ1 |
| UniProt Entry Name | REL1_HUMAN |
| Gene Symbol | RLN1 |
| GeneID | 6013 |
| OMIM | 179730 |
| HGNC | 10026 |
| KEGG | hsa:6013 |
| Ensembl | ENSG00000107018 |
| String | 9606.ENSP00000223862 |
| Molecular Weight | Calculated MW: 21.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |