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Ring Finger Protein 144B (RNF144B) Antibody
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Catalogue No: abx030426
Price:
US$326.25
(Size: 80 µl)
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E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
Research Articles on Ring Finger Protein 144B (RNF144B)
| Target | Ring Finger Protein 144B (RNF144B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q7Z419 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KUA8, B4DZI2, Q5TB85, Q6P4Q0, Q8N3R7, Q9BX38 |
| UniProt Entry Name | R144B_HUMAN |
| Gene Symbol | RNF144B |
| KEGG | hsa:255488 |
| String | 9606.ENSP00000259939 |
| Molecular Weight | Calculated MW: 33.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |