Ring Finger Protein 34 (RNF34) Antibody

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Target	Ring Finger Protein 34 (RNF34)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human RNF34.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q969K3 (UniProt, ExPASy)
UniProt Secondary AC	B7Z933, Q8NG47, Q9H6W8
UniProt Entry Name	RNF34_HUMAN
KEGG	hsa:80196
String	9606.ENSP00000376258
Molecular Weight	Calculated MW: 41.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Cow RNF34.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ring Finger Protein 34 (RNF34)

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