+44 (0) 1223 755950
+1 832 327 7413
Ring Finger Protein 8 (RNF8) Antibody
REQUEST MORE INFO
Catalogue No: abx005509
Price:
US$217.50
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
RNF8 Antibody is a Rabbit Polyclonal antibody against RNF8. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
Research Articles on Ring Finger Protein 8 (RNF8)
| Target | Ring Finger Protein 8 (RNF8) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 230-485 of human RNF8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O76064 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NN24, A8MYC0, B4DPG0, Q53H16, Q5NKW5 |
| UniProt Entry Name | RNF8_HUMAN |
| Gene Symbol | RNF8 |
| GeneID | 9025 |
| NCBI Accession | NP_003949.1 |
| KEGG | hsa:9025 |
| String | 9606.ENSP00000362578 |
| Molecular Weight | Calculated MW: 56 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |