Ring Finger Protein 8 (RNF8) Antibody

RNF8 Antibody is a Rabbit Polyclonal antibody against RNF8. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.

Target	Ring Finger Protein 8 (RNF8)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 230-485 of human RNF8.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O76064 (UniProt, ExPASy)
UniProt Secondary AC	A6NN24, A8MYC0, B4DPG0, Q53H16, Q5NKW5
UniProt Entry Name	RNF8_HUMAN
Gene Symbol	RNF8
GeneID	9025
NCBI Accession	NP_003949.1
KEGG	hsa:9025
String	9606.ENSP00000362578
Molecular Weight	Calculated MW: 56 kDa Observed MW: 60 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ring Finger Protein 8 (RNF8)

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