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X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR) Antibody
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Catalogue No: abx001524
Price:
US$203.00
(Size: 20 µl)
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RPGR Antibody is a Rabbit Polyclonal antibody against RPGR. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008].
Research Articles on X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR)
| Target | X-Linked Retinitis Pigmentosa GTPase Regulator (RPGR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RPGR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92834 (UniProt, ExPASy) |
| UniProt Entry Name | RPGR_HUMAN |
| Gene Symbol | RPGR |
| GeneID | 6103 |
| NCBI Accession | NP_001030025.1 |
| KEGG | hsa:6103 |
| String | 9606.ENSP00000367766 |
| Molecular Weight | Calculated MW: 113 kDa Observed MW: 113 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.01 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |