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Ribonucleoside-Diphosphate Reductase Subunit M2 B (RRM2B) Antibody
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Catalogue No: abx029246
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Research Articles on Ribonucleoside-Diphosphate Reductase Subunit M2 B (RRM2B)
| Target | Ribonucleoside-Diphosphate Reductase Subunit M2 B (RRM2B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 128-157 amino acids from the Central region of human RRM2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q7LG56 (UniProt, ExPASy) |
| Gene Symbol | RRM2B |
| Molecular Weight | Calculated MW: 40.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Monkey RRM2B. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |