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Rhotekin (RTKN) Antibody
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Catalogue No: abx005164
Price:
US$203.00
(Size: 20 µl)
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RTKN Antibody is a Rabbit Polyclonal antibody against RTKN. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Rhotekin (RTKN)
| Target | Rhotekin (RTKN) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 254-513 of human RTKN. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BST9 (UniProt, ExPASy) |
| UniProt Secondary AC | H7BXD4, Q8WVN1, Q96PT6, Q9HB05 |
| UniProt Entry Name | RTKN_HUMAN |
| Gene Symbol | RTKN |
| GeneID | 6242 |
| NCBI Accession | NP_001015056.1 |
| String | 9606.ENSP00000272430 |
| Molecular Weight | Calculated MW: 63 kDa Observed MW: 63 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |