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Runt Related Transcription Factor (RUNX1) Antibody
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Catalogue No: abx117189
Price:
US$522.00
(Size: 100 µl)
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RUNX1 Antibody is a Rabbit Polyclonal antibody against RUNX1. AML1 (also known as Runx1, CBFA2, and PEBP2αB) is a member of the core binding factor (CBF) family of transcription factorsIt is required for normal development of all hematopoietic lineagesAML1 forms a heterodimeric DNA binding complex with its partner protein CBFβ and regulates the expression of cellular genes by binding to promoter and enhancer elementsAML1 is commonly translocated in hematopoietic cancers: chromosomal translocations include t(8;21) AML1-ETO, t(12;21) TEL-AML, and t(8;21) AML-M2Phosphorylation of AML1 on several potential serine and threonine sites, including Ser249, is thought to occur in an Erk-dependent manner.
Research Articles on Runt Related Transcription Factor (RUNX1)
| Target | Runt Related Transcription Factor (RUNX1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide of human RUNX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01196 (UniProt, ExPASy) |
| UniProt Entry Name | RUNX1_HUMAN |
| Gene Symbol | RUNX1 |
| GeneID | 861 |
| KEGG | hsa:861 |
| String | 9606.ENSP00000300305 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |