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Runt Related Transcription Factor 3 (RUNX3) Antibody
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Catalogue No: abx028216
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Runt Related Transcription Factor 3 (RUNX3)
| Target | Runt Related Transcription Factor 3 (RUNX3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 168-197 amino acids from the Central region of human RUNX3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13761 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AJV5, Q12969, Q13760 |
| UniProt Entry Name | RUNX3_HUMAN |
| KEGG | hsa:864 |
| String | 9606.ENSP00000382800 |
| Molecular Weight | Calculated MW: 44.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |