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Runt Related Transcription Factor 3 (RUNX3) Antibody
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Catalogue No: abx005510
Price:
US$348.00
(Size: 60 µl)
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RUNX3 Antibody is a Rabbit Polyclonal antibody against RUNX3. This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Runt Related Transcription Factor 3 (RUNX3)
| Target | Runt Related Transcription Factor 3 (RUNX3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human RUNX3 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13761 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AJV5, Q12969, Q13760 |
| UniProt Entry Name | RUNX3_HUMAN |
| Gene Symbol | RUNX3 |
| GeneID | 864 |
| NCBI Accession | NP_004341.1 |
| KEGG | hsa:864 |
| String | 9606.ENSP00000382800 |
| Molecular Weight | Calculated MW: 44 kDa/45 kDa Observed MW: 44 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
