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S-Phase Kinase Associated Protein 1 (SKP1) Antibody
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Catalogue No: abx217324
Price:
US$406.00
(Size: 100 µg)
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S-Phase Kinase Associated Protein 1 (SKP1) Antibody is a Rabbit Polyclonal antibody for the detection of SKP1. This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein (s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Research Articles on S-Phase Kinase Associated Protein 1 (SKP1)
| Target | S-Phase Kinase Associated Protein 1 (SKP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | S-phase kinase-associated protein 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P63208 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQ97, D3DQ98, P34991, Q8TAY2 |
| UniProt Entry Name | SKP1_HUMAN |
| Gene Symbol | SKP1 |
| GeneID | 6500 |
| OMIM | 601434 |
| HGNC | 10899 |
| KEGG | hsa:6500 |
| Ensembl | ENSG00000113558 |
| String | 9606.ENSP00000231487 |
| Molecular Weight | Observed MW: 19 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |