Ribosomal Protein S6 Kinase Beta-1 (S6K) Antibody

RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.

Target	Ribosomal Protein S6 Kinase Beta-1 (S6K)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 405-434 amino acids from human S6K (RPS6KB1).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23443 (UniProt, ExPASy)
UniProt Secondary AC	B2R779, B4DLT4, B4DTG1, E7ESB8, F6UYM1, Q7Z721
UniProt Entry Name	KS6B1_HUMAN
Gene Symbol	RPS6KB1
KEGG	hsa:6198
String	9606.ENSP00000225577
Molecular Weight	Calculated MW: 59.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow and Rabbit RPS6KB1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ribosomal Protein S6 Kinase Beta-1 (S6K)

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