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Ribosomal Protein S6 Kinase Beta-1 (S6K) Antibody
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Catalogue No: abx031931
Price:
US$326.25
(Size: 80 µl)
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RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Research Articles on Ribosomal Protein S6 Kinase Beta-1 (S6K)
| Target | Ribosomal Protein S6 Kinase Beta-1 (S6K) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 405-434 amino acids from human S6K (RPS6KB1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23443 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R779, B4DLT4, B4DTG1, E7ESB8, F6UYM1, Q7Z721 |
| UniProt Entry Name | KS6B1_HUMAN |
| Gene Symbol | RPS6KB1 |
| KEGG | hsa:6198 |
| String | 9606.ENSP00000225577 |
| Molecular Weight | Calculated MW: 59.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Rabbit RPS6KB1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |