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SUMO-Activating Enzyme Subunit 1 (SAE1) Antibody
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Catalogue No: abx031607
Price:
US$326.25
(Size: 80 µl)
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The dimeric enzyme AOS1 acts as a an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.
Research Articles on SUMO-Activating Enzyme Subunit 1 (SAE1)
| Target | SUMO-Activating Enzyme Subunit 1 (SAE1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human SAE1 (AOS1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UBE0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDP5, B3KMQ2, F5GXX7, G3XAK6, O95717, Q9P020 |
| UniProt Entry Name | SAE1_HUMAN |
| String | 9606.ENSP00000270225 |
| Molecular Weight | Calculated MW: 38.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow SAE1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |