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Scaffold Attachment Factor B1 (SAFB) Antibody
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Catalogue No: abx029479
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
Research Articles on Scaffold Attachment Factor B1 (SAFB)
| Target | Scaffold Attachment Factor B1 (SAFB) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human SAFB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15424 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AV56, B7Z5B6, B7ZLP6, F5H0H3, O60406, Q59HH8 |
| UniProt Entry Name | SAFB1_HUMAN |
| KEGG | hsa:6294 |
| String | 9606.ENSP00000467423 |
| Molecular Weight | Calculated MW: 103 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |