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Synaptosomal-Associated Protein 18 (SAP18) Antibody
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Catalogue No: abx028471
Price:
US$326.25
(Size: 80 µl)
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
Research Articles on Histone Deacetylase Complex Subunit SAP18 (SAP18)
| Target | Histone Deacetylase Complex Subunit SAP18 (SAP18) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 58-86 amino acids from the Central region of human SAP18. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00422 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R494, Q2TTR4, Q6IAW9, Q8N606, Q9UF14, X6RAL5 |
| UniProt Entry Name | SAP18_HUMAN |
| Gene Symbol | SAP18 |
| KEGG | hsa:10284 |
| String | 9606.ENSP00000481842 |
| Molecular Weight | Calculated MW: 17.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow SAP18. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |